I'm working on a project with summarized data from ~40 studies (Excel) involving different protocol variables (durations, intensities, recovery times, frequency, total duration, etc.) and response outcomes conditional on a baseline variable (range ~30-85 units). The aim is to fit a continuous response surface using a hierarchical approach to separate protocol effects from baseline effects, then perform continuous numerical optimization (not grid search) for three objectives: - Total improvement - Improvement per unit time (e.g. per week) - Improvement per unit effort/work Outputs should be fine-grained continuous values rather than rounded study parameters. There are also domain-specific physiological constraints to respect. I'm on a Chromebook with a little Python experience, so Colab-friendly solutions would be ideal. Current candidates I'm considering: PyMC for hierarchical modeling, pymoo + pysamoo for surrogate-assisted MO optimization, SMT for surrogates, or Matlab Global Optimization Toolbox. What is the strongest stack in 2026 for this kind of workflow? Any recommended notebooks, tutorials, or similar applied examples? Are there any AI tools that currently do this without the traditional work of python? Meaning I can upload the spreadsheet give a parameters and it will come up with data.? submitted by /u/BleakReason [link] [Kommentare]
tried to post about /r/Nanogotchi and it was taken down without any reason. Nano (XNO) is a cryptocurrency, and it didn't break any of the rules so? submitted by /u/K1LLerCal [link] [Kommentare]
A meteorite that crashed into a New Jersey home in 2024 is a rare, primitive space rock containing evidence of ancient water.
Microcontrollers with on-die neural processing units (NPUs) have become mainstream, but the system software hosting them has not: production combinations of Zephyr or FreeRTOS with TensorFlow Lite Micro treat AI inference as an application-layer library, leaving memory fragmentation, accelerator-state hygiene, and model-lifecycle guards as recurring application-developer concerns. We present the Phase 1 foundation of SynapticOS, an open-source runtime built on Zephyr that treats inference as a first-class workload. It contributes four cooperating subsystems: (1) a tensor-aware bump allocator with 16-byte DMA-aligned persistent and ephemeral lifetimes sharing a single arena, achieving constant-time allocation (~154 cycles per call, ~78,000 allocations per second at 150 MHz, invariant across tensor sizes) with zero fragmentation by construction; (2) a four-state hardware abstraction layer for the NPU and DSP, implemented by a deterministic software stub (for CI under QEMU) and a Neutron-flavoured backend (for the NXP MCXN947); (3) a three-state model lifecycle registry with duplicate-name detection, idempotent load/unload, and hot-swap guards; and (4) a four-mark cycle-accurate profiler. We evaluate on the NXP FRDM-MCXN947 (dual Cortex-M33 at 150 MHz) and the qemu_cortex_m3 emulator. Build footprints are 67 KB flash / 184 KB SRAM on FRDM (shell, 128 KB arena) and 24 KB flash / 28 KB SRAM on QEMU (no shell, 8 KB arena). End-to-end inference brackets through the deterministic stub kernel measure 1,038 us on FRDM and 781 us on QEMU for a 16x16x3 INT8 input; these are baseline overhead numbers, not Neutron silicon measurements, which arrive with the real SDK invoke path in Phase 2. A 61-test suite across 10 ZTEST suites passes 100% in 6.6 s on the CI emulator path. SynapticOS is released under Apache 2.0 at https://github.com/Dimitrios-Kafetzis/SynapticOS
Ten principles. Real on-chain receipts. A live x402 endpoint: the artifact is never handed over.
Live Claude Code usage in your menu bar, a multi-session cockpit, and an AI that trims your token waste — a precise instrument that never becomes the engine. 100% local, macOS 14+.
Or more broadly: how do you train a machine learning model to capture the nuances of entirely different, conflicting rule sets? I built a XGBoost classification pipeline to answer that. To stress-test the architecture across heterogeneous environments, I applied it to a highly debated and popular hypothetical: cross-universe power scaling The domain is silly. The engineering underneath it isn't. When predicting outcomes across disparate environments, the core challenge is avoiding a lookup table of your own biases. If I manually dictate how these distinct rule sets resolve, the model just learns my heuristics. Here is how I built the architecture to prevent that: Synthetic Data Generation: I engineered an LLM to act as a blind labeler across 2,300+ cross-domain matchups. It only saw character names and their native rule sets, never the underlying stats. This forced my XGBoost classifier to derive its own feature weightings from raw, unbiased outcomes. Catching a Silent Data Leak: My initial accuracy looked suspiciously great. I audited my pipeline and caught a data leak in my train/test split that was mirroring matchups into both sets. I stripped the leak out, expecting the metric to tank. Instead, it went up—hitting 93% on a clean hold-out. The leak had actually been masking a sharper model. Explainable AI (XAI): Raw SHAP values mean nothing to an end-user. I engineered a generation layer that feeds the model's SHAP attributions into an LLM alongside strict domain constraints. The pipeline translates its own mathematical feature importance into a plain-English, logically grounded breakdown of how the conflicting rule sets resolved. It doesn’t just output a winner; it mathematically justifies how it navigated the nuance without hallucinating. Full stack, deployed, and live. Repo: https://github.com/aidentejada/anime-versus-ml Live Endpoint: https://versus.aidentejada.com submitted by /u/iBoomer69 [link] [Kommentare]